Delayed-onset central poststroke pain due to degeneration of the spinothalamic tract following thalamic hemorrhage

From thalamic syndrome to central poststroke pain.

Central Pain Due to Spinothalamic Tract Injury by Head Trauma Caused by Falling Object

female who suffered trauma from a falling large box (100 cm×30 cm×30 cm) that hit the vertex of her head while seated in a subway car. The patient experienced loss of consciousness for several minutes, and post-traumatic amnesia for several minutes, with a Glasgow Coma Scale score of 15. She experienced severe bursting pain in her head, neck and upper back immediately after the head trauma; and...

Maladaptive homeostatic plasticity in a rodent model of central pain syndrome: thalamic hyperexcitability after spinothalamic tract lesions.

Central pain syndrome (CPS) is defined as pain associated with a lesion of the CNS and is a common consequence of spinal cord injuries. We generated a rodent model of CPS by making unilateral electrolytic or demyelinating lesions centered on the spinothalamic tract in rats. Thermal hyperalgesia and mechanical allodynia occurred in both hind paws and forepaws by 7 d postlesion and were maintaine...

Delayed Consecutive Contralateral Thalamic Hemorrhage after Spontaneous Thalamic Hemorrhage

Simultaneous or subsequent bilateral thalamic hemorrhagic events have ranged from 12 to 19 in prior reports, with a time lag between bilateral thalamic hemorrhage of up to two days. Herein, we report the first case of delayed (17 days) consecutive contralateral thalamic hemorrhage after spontaneous first thalamic hemorrhage. A 65-year-old female initially presented with a drowsy mentality with ...

Global aphasia due to left thalamic hemorrhage.

Global aphasia is an acquired language disorder characterized by severe impairments in all modalities of language. The specific sites of injury commonly include Wernike's and Broca's areas and result from large strokes--particularly those involving the internal carotid or middle cerebral arteries. Rarely, deep subcortical lesions may cause global aphasia. We present three cases with global apha...